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TSND-201 (Methylone) for the Treatment of PTSD: Improvements across each CAPS-5 Cluster and Anxiety Symptoms from the Open-Label Portion of the IMPACT-1 Study
Poster Presentation

TSND-201 (Methylone) for the Treatment of PTSD: Improvements across each CAPS-5 Cluster and Anxiety Symptoms from the Open-Label Portion of the IMPACT-1 Study

American College of Neuropsychopharmacology (ACNP), December 2024. 
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Summary of poster presentation:

  • TSND-201 demonstrated rapid, robust, and consistent improvements across each PTSD symptom domain (Intrusion, Avoidance, Cognition and Mood, Arousal and Reactivity).
  • Rapid and durable improvement on anxiety symptoms occurred concurrently with PTSD symptom improvement.
  • TSND-201 was generally safe and well tolerated; the most common adverse events (AEs) were headache and decreased appetite.
  • Randomized, placebo-controlled study is ongoing, with results expected in Q2 2025.

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